The in vivo and in vitro corrosion behavior of MgO/Mg-Zn-Ca composite with different Zn/Ca ratio

Shuquan Zhang; Chaokun Tang; Jiangtao Feng; Qi Wang; Chenguang Li; Weihao Zhang; Fengxin Zhou; Feng Xue; Baoshan Xu; Shaoyuan Lyu; Minfang Chen; Minfang Chen; Minfang Chen; Hao Wang

doi:10.3389/fbioe.2023.1222722

Frontiers in Bioengineering and Biotechnology (Jun 2023)

The in vivo and in vitro corrosion behavior of MgO/Mg-Zn-Ca composite with different Zn/Ca ratio

Shuquan Zhang,
Chaokun Tang,
Jiangtao Feng,
Qi Wang,
Chenguang Li,
Weihao Zhang,
Fengxin Zhou,
Feng Xue,
Baoshan Xu,
Shaoyuan Lyu,
Minfang Chen,
Minfang Chen,
Minfang Chen,
Hao Wang

Affiliations

Shuquan Zhang: Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China
Chaokun Tang: School of Materials Science and Engineering, Tianjin University of Technology, Tianjin, China
Jiangtao Feng: Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China
Qi Wang: Department of Orthopedics, Integrated Chinese and Western Medicine Hospital, Tianjin University, Tianjin, China
Chenguang Li: Department of Orthopedics, Integrated Chinese and Western Medicine Hospital, Tianjin University, Tianjin, China
Weihao Zhang: Department of Orthopedics, Integrated Chinese and Western Medicine Hospital, Tianjin University, Tianjin, China
Fengxin Zhou: Department of Orthopedics, Integrated Chinese and Western Medicine Hospital, Tianjin University, Tianjin, China
Feng Xue: Department of Orthopedics, Integrated Chinese and Western Medicine Hospital, Tianjin University, Tianjin, China
Baoshan Xu: Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China
Shaoyuan Lyu: School of Materials Science and Engineering, Tianjin University of Technology, Tianjin, China
Minfang Chen: School of Materials Science and Engineering, Tianjin University of Technology, Tianjin, China
Minfang Chen: National Demonstration Center for Experimental Function Materials Education, Tianjin, China
Minfang Chen: Key Laboratory of Display Materials and Photoelectric Device (Ministry of Education), Tianjin, China
Hao Wang: Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China

DOI: https://doi.org/10.3389/fbioe.2023.1222722
Journal volume & issue: Vol. 11

Abstract

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The effect of Zn/Ca ratio on the corrosion behavior of Mg–3Zn-0.2Ca-1.0MgO (3ZX) and Mg–1Zn-0.2Ca-1.0MgO (ZX) was investigated on the as-extruded specimens. Microstructure observations revealed that the low Zn/Ca ratio led to the grain growth from 1.6 µm in 3ZX to 8.1 µm in ZX. At the same time, the low Zn/Ca ratio changed the nature of second phase from the existence of Mg-Zn and Ca2Mg6Zn3 phases in 3ZX to the dominated Ca2Mg6Zn3 phase in ZX. The local galvanic corrosion caused by the excessive potential difference was alleviated obviously due to the missing of MgZn phase in ZX. Besides, the in vivo experiment also showed that ZX composite exhibited a good corrosion performance and the bone tissue around the implant grew well.

Published in Frontiers in Bioengineering and Biotechnology

ISSN: 2296-4185 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Technology: Chemical technology: Biotechnology
Website: http://www.frontiersin.org/bioengineering_and_biotechnology

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