Intensity-dependent stimulation of leukocyte telomerase activity by endurance exercise – a pilot study

Abstract

Exercise induces telomerase activity and regulates shelterin expression. These effects are believed to preserve telomeres. However, the impact of exercise intensity on telomerase and shelterins has not been studied systematically. This pilot study investigated the kinetics of leukocyte telomerase activity (LTA) and the expression of telomere-related genes in response to exercise at different intensities.

Keywords

• cellular senescence
• physical exercise
• shelterins
• telomerase
• telomeres