New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany

Abstract

We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.

Keywords

• COVID-19
• respiratory infections
• severe acute respiratory syndrome coronavirus 2
• SARS-CoV-2
• SARS
• coronavirus disease