MicroRNAs in Sarcopenia: A Systematic Review

Katsunori Yanai; Shohei Kaneko; Hiroki Ishii; Akinori Aomatsu; Akinori Aomatsu; Kiyonori Ito; Keiji Hirai; Susumu Ookawara; Kenichi Ishibashi; Yoshiyuki Morishita

doi:10.3389/fmed.2020.00180

Frontiers in Medicine (May 2020)

MicroRNAs in Sarcopenia: A Systematic Review

Katsunori Yanai,
Shohei Kaneko,
Hiroki Ishii,
Akinori Aomatsu,
Akinori Aomatsu,
Kiyonori Ito,
Keiji Hirai,
Susumu Ookawara,
Kenichi Ishibashi,
Yoshiyuki Morishita

Affiliations

Katsunori Yanai: Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Shohei Kaneko: Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Hiroki Ishii: Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Akinori Aomatsu: Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Akinori Aomatsu: Division of Intensive Care Unit, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Kiyonori Ito: Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Keiji Hirai: Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Susumu Ookawara: Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Kenichi Ishibashi: Department of Medical Physiology, Meiji Pharmaceutical University, Tokyo, Japan
Yoshiyuki Morishita: Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan

DOI: https://doi.org/10.3389/fmed.2020.00180
Journal volume & issue: Vol. 7

Abstract

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Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies have shown that miRNAs play pivotal roles in the development of sarcopenia. Therefore, this systematic review focuses on miRNAs that regulate sarcopenia.

Published in Frontiers in Medicine

ISSN: 2296-858X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.frontiersin.org/journals/medicine

About the journal

Abstract

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