Nature Communications (Jul 2021)

A fructose/H+ symporter controlled by a LacI-type regulator promotes survival of pandemic Vibrio cholerae in seawater

  • Yutao Liu,
  • Bin Liu,
  • Tingting Xu,
  • Qian Wang,
  • Wendi Li,
  • Jialin Wu,
  • Xiaoyu Zheng,
  • Bin Liu,
  • Ruiying Liu,
  • Xingmei Liu,
  • Xi Guo,
  • Lu Feng,
  • Lei Wang

DOI
https://doi.org/10.1038/s41467-021-24971-3
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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The bacterium Vibrio cholerae can colonize the human intestine and cause cholera, but spends much of its life cycle in seawater. Here, Liu et al. identify a fructose uptake system that is important for the growth of the bacteria in seawater, where fructose concentrations are low.