Structure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE
Dr. Anton Zalygin,
Dr. Daria Solovyeva,
Ivan Vaskan,
Dr. Stephen Henry,
Dr. Marcel Schaefer,
Dr. Pavel Volynsky,
Dr. Alexander Tuzikov,
Dr. Elena Korchagina,
Dr. Ivan Ryzhov,
Dr. Alexey Nizovtsev,
Dr. Konstantin Mochalov,
Prof. Roman Efremov,
Dr. Eleonora Shtykova,
Dr. Vladimir Oleinikov,
Prof. Nicolai Bovin
Affiliations
Dr. Anton Zalygin
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Dr. Daria Solovyeva
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Ivan Vaskan
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Dr. Stephen Henry
School of Engineering Computer & Mathematical Sciences Auckland University of Technology Auckland 1010 New Zealand
Dr. Marcel Schaefer
School of Engineering Computer & Mathematical Sciences Auckland University of Technology Auckland 1010 New Zealand
Dr. Pavel Volynsky
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Dr. Alexander Tuzikov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Dr. Elena Korchagina
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Dr. Ivan Ryzhov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Dr. Alexey Nizovtsev
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Dr. Konstantin Mochalov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Prof. Roman Efremov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Dr. Eleonora Shtykova
Shubnikov Institute of Crystallography of Federal Scientific Research Centre 'Crystallography and Photonics' of Russian Academy of Sciences Moscow 119333 Russian Federation
Dr. Vladimir Oleinikov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Prof. Nicolai Bovin
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
Abstract Invited for this month's cover is the group of Prof. Nicolai Bovin from the Russian Academy of Sciences. The cover picture shows how a biotin residue initially hidden in a monolayer formed on the surface of a material by biot‐CMG‐DOPE (see top left) is pulled out of the layer by the streptavidin molecule (Str) that has come close to it (see below). This can be considered as a model of certain events (in particular, cis protein‐ligand interactions) occurring on the surface of a living cell when it is necessary to hide the ligand from undesirable interactions, but leave the possibility of its recognition by a high‐affinity protein. The picture is inspired by the legendary Yellow Submarine cartoon. Read the full text of their Full Paper at 10.1002/open.201900276.
