ChemistryOpen (Jun 2020)

Structure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE

  • Dr. Anton Zalygin,
  • Dr. Daria Solovyeva,
  • Ivan Vaskan,
  • Dr. Stephen Henry,
  • Dr. Marcel Schaefer,
  • Dr. Pavel Volynsky,
  • Dr. Alexander Tuzikov,
  • Dr. Elena Korchagina,
  • Dr. Ivan Ryzhov,
  • Dr. Alexey Nizovtsev,
  • Dr. Konstantin Mochalov,
  • Prof. Roman Efremov,
  • Dr. Eleonora Shtykova,
  • Dr. Vladimir Oleinikov,
  • Prof. Nicolai Bovin

DOI
https://doi.org/10.1002/open.202000139
Journal volume & issue
Vol. 9, no. 6
pp. 640 – 640

Abstract

Read online

Abstract Invited for this month's cover is the group of Prof. Nicolai Bovin from the Russian Academy of Sciences. The cover picture shows how a biotin residue initially hidden in a monolayer formed on the surface of a material by biot‐CMG‐DOPE (see top left) is pulled out of the layer by the streptavidin molecule (Str) that has come close to it (see below). This can be considered as a model of certain events (in particular, cis protein‐ligand interactions) occurring on the surface of a living cell when it is necessary to hide the ligand from undesirable interactions, but leave the possibility of its recognition by a high‐affinity protein. The picture is inspired by the legendary Yellow Submarine cartoon. Read the full text of their Full Paper at 10.1002/open.201900276.