Oil Red O positive vacuolated blasts in a case of CD45 negative, CD19 negative B-lymphoblastic leukemia

Diana O. Treaba, MD; Allison Chen; Chad Ellermeier, MD; Bradley DeNardo, MD; Rachel Altura, MD

doi:10.1016/j.ehpc.2015.12.005

Human Pathology: Case Reports (Dec 2016)

Oil Red O positive vacuolated blasts in a case of CD45 negative, CD19 negative B-lymphoblastic leukemia

Diana O. Treaba, MD,
Allison Chen,
Chad Ellermeier, MD,
Bradley DeNardo, MD,
Rachel Altura, MD

Affiliations

Diana O. Treaba, MD: The Warren Alpert Medical School at Brown University, Providence, RI, USA
Allison Chen: The Warren Alpert Medical School at Brown University, Providence, RI, USA
Chad Ellermeier, MD: The Warren Alpert Medical School at Brown University, Providence, RI, USA
Bradley DeNardo, MD: The Warren Alpert Medical School at Brown University, Providence, RI, USA
Rachel Altura, MD: The Warren Alpert Medical School at Brown University, Providence, RI, USA

DOI: https://doi.org/10.1016/j.ehpc.2015.12.005
Journal volume & issue: Vol. 6, no. C
pp. 1 – 7

Abstract

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B-lymphoblastic leukemia is a clonal hematopoietic disorder of precursors B-lymphoblasts being most frequently encountered in children. Expression of CD19, a pan B-cell marker is noted in the majority of the cases with lack of CD19 expression being extremely rarely reported in the medical literature. We report the very rare case of a B-lymphoblastic leukemia with a triple negative immunophenotype: CD19 negative, CD45 negative and CD10 negative with vacuolated lymphoblasts and an aleukemic presentation in a 20-year-old man.

Published in Human Pathology: Case Reports

ISSN: 2214-3300 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Pathology
Website: http://www.journals.elsevier.com/human-pathology-case-reports/

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