Frontiers in Medicine (Nov 2023)
Management of psoriatic arthritis: a consensus opinion by expert rheumatologists
- Salvatore D’Angelo,
- Fabiola Atzeni,
- Maurizio Benucci,
- Gerolamo Bianchi,
- Fabrizio Cantini,
- Roberto Felice Caporali,
- Roberto Felice Caporali,
- Giorgio Carlino,
- Francesco Caso,
- Alberto Cauli,
- Francesco Ciccia,
- Maria Antonietta D’Agostino,
- Lorenzo Dagna,
- Lorenzo Dagna,
- Christian Dejaco,
- Christian Dejaco,
- Oscar Massimiliano Epis,
- Maria Grazia Ferrucci,
- Franco Franceschini,
- Franco Franceschini,
- Enrico Fusaro,
- Marco Gabini,
- Roberto Gerli,
- Roberto Giacomelli,
- Roberto Giacomelli,
- Marcello Govoni,
- Elisa Gremese,
- Giuliana Guggino,
- Annamaria Iagnocco,
- Florenzo Iannone,
- Bruno Laganà,
- Ennio Lubrano,
- Carlomaurizio Montecucco,
- Rosario Peluso,
- Roberta Ramonda,
- Maurizio Rossini,
- Carlo Salvarani,
- Gian Domenico Sebastiani,
- Marco Sebastiani,
- Carlo Selmi,
- Carlo Selmi,
- Enrico Tirri,
- Antonio Marchesoni,
- Antonio Marchesoni
Affiliations
- Salvatore D’Angelo
- Rheumatology Department of Lucania, San Carlo Hospital of Potenza, Potenza, Italy
- Fabiola Atzeni
- Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy
- Maurizio Benucci
- Rheumatology Unit, S. Giovanni di Dio Hospital, Florence, Italy
- Gerolamo Bianchi
- Division of Rheumatology, Department of Medical Specialties, Azienda Sanitaria Locale 3 Genovese, Genova, Italy
- Fabrizio Cantini
- Private Practice, Prato, Italy
- Roberto Felice Caporali
- Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan, Italy
- Roberto Felice Caporali
- Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
- Giorgio Carlino
- Rheumatology Service, ASL LE-DSS Casarano and Gallipoli, Gallipoli, Italy
- Francesco Caso
- Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy
- Alberto Cauli
- 0Rheumatology Unit, Department of Medicine and Public Health, AOU and University of Cagliari, Cagliari, Italy
- Francesco Ciccia
- 1Rheumatology Section, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy
- Maria Antonietta D’Agostino
- 2Department of Rheumatology, Catholic University of Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, IRCSS, Rome, Italy
- Lorenzo Dagna
- 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), San Raffaele Scientific Institute, Milan, Italy
- Lorenzo Dagna
- 4School of Medicine, Vita-Salute San Raffaele University, Milan, Italy
- Christian Dejaco
- 5Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria
- Christian Dejaco
- 6Department of Rheumatology, Teaching Hospital of the Paracelsius Medical University, Brunico Hospital (ASAA-SABES), Brunico, Italy
- Oscar Massimiliano Epis
- 7Division of Rheumatology, Multispecialist Medical Department, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
- Maria Grazia Ferrucci
- 8Department of Rheumatology, Azienda Ospedaliera Rummo Benevento, Benevento, Italy
- Franco Franceschini
- 9Rheumatology and Clinical Immunology Unit, Dipartimento Continuità di Cure e Fragilità, ASST Spedali Civili di Brescia, Brescia, Italy
- Franco Franceschini
- 0Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
- Enrico Fusaro
- 1Rheumatology Unit, University Hospital AOU Città della Salute e della Scienza di Torino, Turin, Italy
- Marco Gabini
- 2Rheumatology Unit, Santo Spirito Hospital, Pescara, Italy
- Roberto Gerli
- 3Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy
- Roberto Giacomelli
- 4Research Unit of Immuno-Rheumatology, Department of Medicine, School of Medicine, University of Rome "Campus Biomedico", Rome, Italy
- Roberto Giacomelli
- 5Fondazione Policlinico Campus Bio-Medico, Rome, Italy
- Marcello Govoni
- 6Rheumatology Unit, Department of Medical Sciences, Azienda Ospedaliero-Universitaria S. Anna-Ferrara, University of Ferrara, Ferrara, Italy
- Elisa Gremese
- 7Clinical Immunology Unit, Department of Geriatrics, Orthopedics and Rheumatology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Catholic University of the Sacred Heart, Rome, Italy
- Giuliana Guggino
- 8PROMISE, Università degli studi di Palermo, Palermo, Italy
- Annamaria Iagnocco
- 9Academic Rheumatology Centre, Department of Clinical and Biological Sciences, Università degli Studi di Torino, Turin, Italy
- Florenzo Iannone
- 0DiMePRe-J, Rheumatology Unit, Università degli studi di Bari “Aldo Moro”, Bari, Italy
- Bruno Laganà
- 1Department of Clinical and Molecular Medicine, Sapienza University of Rome-S. Andrea University Hospital, Rome, Italy
- Ennio Lubrano
- 2Academic Rheumatology Unit, Department of Medicine and Health Sciences "Vincenzo Tiberio", Università Degli Studi del Molise, Campobasso, Italy
- Carlomaurizio Montecucco
- 3Department of Internal Medicine and Therapeutics, Rheumatology Unit, University of Pavia, IRCCS Policlinico S. Matteo, Pavia, Italy
- Rosario Peluso
- 4Department of Clinical Medicine and Surgery, School of Medicine, University Federico II of Naples, Naples, Italy
- Roberta Ramonda
- 5Rheumatology Unit+ EULAR Center of Excellence in Rheumatology, Department of Medicine-DIMED, University of Padova, Padua, Italy
- Maurizio Rossini
- 6Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy
- Carlo Salvarani
- 7Azienda USL-IRCCS di Reggio Emilia, Università di Modena e Reggio Emilia, Reggio Emilia, Italy
- Gian Domenico Sebastiani
- 8Rheumatology, Azienda Ospedaliera San Camillo Forlanini, Rome, Italy
- Marco Sebastiani
- 9Rheumatology Unit, CHIMOMO, University of Modena and Reggio Emilia, Modena, Italy
- Carlo Selmi
- 0Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy
- Carlo Selmi
- 1Department of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center-IRCCS, Rozzano, Italy
- Enrico Tirri
- 2Rheumatology Unit, Ospedale del Mare, Naples, Italy
- Antonio Marchesoni
- 3Rheumatology, Humanitas San Pio X, Milan, Italy
- Antonio Marchesoni
- 4Ospedale S. Maria Nuova, Reggio Emilia, Italy
- DOI
- https://doi.org/10.3389/fmed.2023.1327931
- Journal volume & issue
-
Vol. 10
Abstract
BackgroundPsoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease involving several articular and extra-articular structures. Despite the important progresses recently made in all of the aspects of this disease, its management is still burdened by unresolved issues. The aim of this exercise was to provide a set of statements that may be helpful for the management of PsA.MethodsA group of 38 Italian rheumatologists with recognized expertise in PsA selected and addressed the following four topics: “early PsA,” “axial-PsA,” “extra-articular manifestations and comorbidities,” “therapeutic goals.” Relevant articles from the literature (2016–2022) were selected by the experts based on a PubMed search. A number of statements for each topic were elaborated.ResultsNinety-four articles were selected and evaluated, 68 out of the 1,114 yielded by the literature search and 26 added by the Authors. Each of the four topic was subdivided in themes as follows: transition from psoriasis to PsA, imaging vs. CASPAR criteria in early diagnosis, early treatment for “early PsA”; axial-PsA vs. axialspondyloarthritis, diagnosis, clinical evaluation, treatment, standard radiography vs. magnetic resonance imaging for “axial PsA”; influence of inflammatory bowel disease on the therapeutic choice, cardiovascular comorbidity, bone damage, risk of infection for “comorbidities and extra-articular manifestations”; target and tools, treat-to-target strategy, role of imaging for “therapeutic goals.” The final document consisted of 49 statements.DiscussionThe final product of this exercise is a set of statements concerning the main issues of PsA management offering an expert opinion for some unmet needs of this complex disease.
Keywords
- psoriatic arthritis
- chronic inflammatory musculoskeletal disease
- comorbidities
- extra-articular manifestations
- diagnosis
- treatment