Nature Communications (Nov 2021)

Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition

  • K. E. Huus,
  • T. T. Hoang,
  • A. Creus-Cuadros,
  • M. Cirstea,
  • S. L. Vogt,
  • K. Knuff-Janzen,
  • P. J. Sansonetti,
  • P. Vonaesch,
  • B. B. Finlay

DOI
https://doi.org/10.1038/s41467-021-27191-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

Read online

Malnourished children experience a high burden of intestinal pathogens that exacerbate growth stunting, and preventing this pathogen overgrowth has proved challenging. Here the authors show that diet-specific bacterial crossfeeding contributes to the overgrowth of intestinal pathogens during child malnutrition.