Ratiometric Fluorescence Probe Based on Deep-Red Emissive CdTe Quantum Dots and Eu<sup>3+</sup> Hybrid for Oxytetracycline Detection
Siyi Tan,
Qin Wang,
Qiuxia Tan,
Shaojing Zhao,
Lei Huang,
Benhua Wang,
Xiangzhi Song,
Minhuan Lan
Affiliations
Siyi Tan
Surgical Department of Medical Laboratory, Higentec Co., Ltd., 618 Heping Road, Changsha 410125, China
Qin Wang
Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
Qiuxia Tan
Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
Shaojing Zhao
Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
Lei Huang
Hunan Prevention and Treatment Institute for Occupational Diseases, 612 New West Road, Changsha 410007, China
Benhua Wang
Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
Xiangzhi Song
Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
Minhuan Lan
Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
Oxytetracycline (OTC) is an environmental pollutant caused by the abuse of antibiotics, and its content in water is closely related to human health. Therefore, the development of a simple, rapid, and accurate method to detect OTC has become desirable. In this work, a ratiometric fluorescence probe based on deep red emissive CdTe quantum dots (QDs) modified by mercaptopropionic acid and Eu3+ is developed to accurately and rapidly detect OTC in water. After the addition of OTC, the photoluminescence intensity of CdTe QDs at 698 nm remains almost unchanged, while the peak at 617 nm intensifies within 40 s due to the coordination of Eu3+ with OTC. An excellent linear relationship is present between the photoluminescence intensity ratio of I617/I698 and the concentration of OTC. The limit of detection of the probe towards OCT is 5.4 nM. In addition, the probe shows good selectivity and anti-interference ability for OTC in the presence of other antibiotics, including other antibiotics, ions, and amino acids. The probe has been successfully applied to detect OTC in actual samples, demonstrating its potential for environmental application.
