Frontiers in Physiology (May 2022)
New Perspectives for Postmortem Human Satellite Cells of Different Embryological Origin
- Tiziana Pietrangelo,
- Tiziana Pietrangelo,
- Roberto Demontis,
- Carmen Santangelo,
- Carmen Santangelo,
- Niccolò Pini,
- Martina Bonelli,
- Enrica Rosato,
- Paola Roberti,
- Marcello Locatelli,
- Angela Tartaglia,
- Lorenzo Marramiero,
- Lorenzo Marramiero,
- Vittore Verratti,
- Danilo Bondi,
- Danilo Bondi,
- Stefania Fulle,
- Stefania Fulle,
- Ernesto D’Aloja,
- Cristian D’Ovidio
Affiliations
- Tiziana Pietrangelo
- Laboratory of Functional Evaluation and Cellular Physiology, Department Neuroscience Imaging and Clinical Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Tiziana Pietrangelo
- Interuniversity Institute of Myology (IIM), Chieti, Italy
- Roberto Demontis
- Department of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, Italy
- Carmen Santangelo
- Laboratory of Functional Evaluation and Cellular Physiology, Department Neuroscience Imaging and Clinical Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Carmen Santangelo
- Interuniversity Institute of Myology (IIM), Chieti, Italy
- Niccolò Pini
- Laboratory of Functional Evaluation and Cellular Physiology, Department Neuroscience Imaging and Clinical Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Martina Bonelli
- Department of Medicine and Aging Sciences, Section of Legal Medicine, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Enrica Rosato
- Department of Pharmacy, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Paola Roberti
- Department of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, Italy
- Marcello Locatelli
- Department of Pharmacy, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Angela Tartaglia
- Department of Pharmacy, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Lorenzo Marramiero
- Laboratory of Functional Evaluation and Cellular Physiology, Department Neuroscience Imaging and Clinical Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Lorenzo Marramiero
- Interuniversity Institute of Myology (IIM), Chieti, Italy
- Vittore Verratti
- Department of Psychological, Health and Territorial Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Danilo Bondi
- Laboratory of Functional Evaluation and Cellular Physiology, Department Neuroscience Imaging and Clinical Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Danilo Bondi
- Interuniversity Institute of Myology (IIM), Chieti, Italy
- Stefania Fulle
- Laboratory of Functional Evaluation and Cellular Physiology, Department Neuroscience Imaging and Clinical Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- Stefania Fulle
- Interuniversity Institute of Myology (IIM), Chieti, Italy
- Ernesto D’Aloja
- Department of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, Italy
- Cristian D’Ovidio
- Department of Medicine and Aging Sciences, Section of Legal Medicine, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
- DOI
- https://doi.org/10.3389/fphys.2022.886149
- Journal volume & issue
-
Vol. 13
Abstract
Human postmortem skeletal muscles are a unique source of satellite cells for skeletal muscle regenerative studies. Presomite and somite satellite cells obtained by postmortem muscles have been established as populations of human skeletal muscle precursor cells able to proliferate and differentiate in vitro. It is extremely interesting to have access to a large amount of postmortem human skeletal muscle precursor cells, especially from craniofacial as well as limb skeletal muscles in order to evaluate their potential application not only for the fundamental understanding of muscle physiology and diseases but also for drug testing in a challenging 3D-shaping muscles like skeletal muscle microphysiological systems.
Keywords
- satellite cells
- skeletal muscle regeneration
- postmortem
- presomitic muscles
- somitic muscles
- embryonic origin
