Nature Communications (Jun 2021)

Fast and strong amplifiers of natural selection

  • Josef Tkadlec,
  • Andreas Pavlogiannis,
  • Krishnendu Chatterjee,
  • Martin A. Nowak

DOI
https://doi.org/10.1038/s41467-021-24271-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 6

Abstract

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Population structure can influence the probability of and time to fixation of new mutants. Here, Tkadlec et al. demonstrate mathematically that structures that increase fixation probability necessarily slow fixation, but also identify amplifying structures with minimal reductions in fixation time.