Indian Journal of Ophthalmology (Jan 2019)

Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature

  • Kaustubh Mulay,
  • Vikas Menon,
  • Sumeet Lahane,
  • Mukesh Sharma,
  • Santosh G Honavar

DOI
https://doi.org/10.4103/ijo.IJO_1745_18
Journal volume & issue
Vol. 67, no. 8
pp. 1374 – 1377

Abstract

Read online

Sweat gland neoplasms are rare adnexal tumors that pose a diagnostic challenge for both, ophthalmologists and pathologists. Endocrine, mucin producing sweat gland carcinoma (EMPSGC), considered to be analogous to the solid papillary mammary carcinoma is one such tumor. It usually affects elderly, is more frequent in women and has a predilection for skin of the eyelid. Although it has an indolent clinical course, EMPSGC is believed to be a precursor of the invasive mucinous carcinoma and has a potential for local recurrence. We report a series of 10 biopsy-proven EMPSGCs with their immunohistochemical features and review the literature.

Keywords