Nature Communications (Jun 2021)

Smart-watch-programmed green-light-operated percutaneous control of therapeutic transgenes

  • Maysam Mansouri,
  • Marie-Didiée Hussherr,
  • Tobias Strittmatter,
  • Peter Buchmann,
  • Shuai Xue,
  • Gieri Camenisch,
  • Martin Fussenegger

DOI
https://doi.org/10.1038/s41467-021-23572-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

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Wearable smart devices often have green light diodes to monitor health. Here the authors use this to control a light-activated genetic switch for GLP1 production in diabetic mice.