In Silico-Guided Rational Drug Design and Semi-synthesis of C(2)-Functionalized Huperzine A Derivatives as Acetylcholinesterase Inhibitors

• Shisanupong Anukanon,
• Pornkanok Pongpamorn,
• Wareepat Tiyabhorn,
• Jaruwan Chatwichien,
• Worawat Niwetmarin,
• Richard B. Sessions,
• Somsak Ruchirawat,
• Nopporn Thasana

Affiliations

Shisanupong Anukanon

Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand

Pornkanok Pongpamorn

Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand

Wareepat Tiyabhorn

Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand

Jaruwan Chatwichien

Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand

Worawat Niwetmarin

Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand

Richard B. Sessions

School of Biochemistry, University of Bristol, Bristol, United Kingdom

Somsak Ruchirawat

Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand

Nopporn Thasana

Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand