Prophylactic adnexectomy in BRCA1 and BRCA2 gene mutation carriers (а review of literature)

Abstract

The development of genetics in the study of predisposition to malignancies, to ovarian and breast cancers in particular, as well as the experi- ence of prophylactic surgery to reduce the risks of these diseases have permitted prophylactic bilateral tube ovariectomy to be used as a main technique in BRCA1 and BRCА2 gene mutation carriers. The purpose of this investigation is to demonstrate key studies in this area.

Keywords

• brca1 and brca2 mutation
• prophylactic tube ovariectomy