Clinical Epidemiology and Global Health (Jul 2022)

Epidemiological and clinical features of syphilis in the 21st century: A seven-year observational retrospective study of outpatients

  • Biagio Pinchera,
  • Giulio Viceconte,
  • Antonio Riccardo Buonomo,
  • Emanuela Zappulo,
  • Simona Mercinelli,
  • Nicola Schiano Moriello,
  • Letizia Cattaneo,
  • Riccardo Scotto,
  • Agnese Giaccone,
  • Roberta Cristina Avallone,
  • Grazia Tosone,
  • Ivan Gentile

Journal volume & issue
Vol. 16
p. 101100

Abstract

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Background: Syphilis represents a current and emerging public health problem. The number of newly diagnosed cases of syphilis ranges from 5 to 12 million worldwide each year, albeit with differences in distribution and trend. Methods: In this study we evaluated the trend of syphilis cases in a tertiary university hospital of Southern Italy to determine whether the clinical manifestations and/or risk factors have changed over time in relation to the patient's demographic and behavioural characteristics. Results: In our experience we observed an increase in the number of cases of syphilis especially among young people and few subjects undergo screening after at-risk sexual intercourse and/or upon medical advice. Conclusions: About syphilis new emerging features were observed. There was a need to pay more attention to screening, prevention and information for this pathology.

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