Медицинский вестник Юга России (Mar 2015)

DIAGNOSTIC VALUE OF HOMOCYSTEINE AND INDICATORS OF LIPID METABOLISM IN PATIENTS WITH EARLY RECOVERY PERIOD OF ISCHEMIC STROKE

  • T. V. Myronenko,
  • L. V. Yakovlieva,
  • R. V. Kanivets

DOI
https://doi.org/10.21886/2219-8075-2015-1-61-66
Journal volume & issue
Vol. 0, no. 1
pp. 61 – 66

Abstract

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Purpose: to evaluate the diagnostic value of plasma homocysteine and lipoprotein cholesterol fractions in dynamics of neurological disorders in the(не нужно) early recovery period of ischemic stroke.Materials and Methods: 70 patients with ischemic stroke prescription of 1-4 months and 20 control subjects with atherosclerotic encephalopathy I st were examined. Methods of observation of patients included some clinical, neurological, neuroimaging, laboratory and statistical tests.Results: the autonomic dysfunction and focal neurological defi citwere predominated in a structure of the revealed neurological symptoms. An increase of blood levels of total cholesterol, LDL, VLDL and IA, GC were registered in all patients in comparison with control group (p <0,001).Summary: the study found out that in the early recovery period of ischemic stroke is determined by the increase in blood levels of total cholesterol, low-density lipoprotein cholesterol and very low density lipoproteins, triglycerides, atherogenic index, which is combined with an increase in plasma homocysteine. A direct correlation between the index of atherogenic blood and plasma homocysteine levels; homocysteine blood levels and low density lipoprotein cholesterol in patients which has a certain diagnostic and possibly prognostic value.

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