This manuscript details the modifications made to the HPLC assay method described in the USP monograph for Acetazolamide Compounded Oral Suspension. • The method was modified to allow the quantification of acetazolamide in two new suspension vehicles: Oral Mix and Oral Mix SF; • It was validated for linearity, accuracy, precision and specificity; • It was demonstrated stability-indicating and suitable for use in a stability study using these vehicles.
