Applied Sciences (Feb 2024)

An Overview of Biopolymers for Drug Delivery Applications

  • Ocsana Opriș,
  • Cristina Mormile,
  • Ildiko Lung,
  • Adina Stegarescu,
  • Maria-Loredana Soran,
  • Albert Soran

DOI
https://doi.org/10.3390/app14041383
Journal volume & issue
Vol. 14, no. 4
p. 1383

Abstract

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Nowadays, drug delivery has an important role in medical therapy. The use of biopolymers in developing drug delivery systems (DDSs) is increasingly attracting attention due to their remarkable and numerous advantages, in contrast to conventional polymers. Biopolymers have many advantages (biodegradability, biocompatibility, renewability, affordability, and availability), which are extremely important for developing materials with applications in the biomedical field. Additionally, biopolymers are appropriate when they improve functioning and have a number of positive effects on human life. Therefore, this review presents the most used biopolymers for biomedical applications, especially in drug delivery. In addition, by combining different biopolymers DDSs with tailored functional properties (e.g., physical properties, biodegradability) can be developed. This review summarizes and provides data on the progress of research on biopolymers (chitosan, alginate, starch, cellulose, albumin, silk fibroin, collagen, and gelatin) used in DDSs, their preparation, and mechanism of action.

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