Forensic Analysis of 9 Poisoning Death Cases Caused by Oral Administration of Diphenidol
YANG Liu,
XIANG Ping,
DENG Hong-xiao,
QIANG Huo-sheng,
DANG Yong-hui,
SHI Yan,
SHEN Bao-hua
Affiliations
YANG Liu
Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
XIANG Ping
Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
DENG Hong-xiao
Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
QIANG Huo-sheng
Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
DANG Yong-hui
School of Forensic Medicine, Health Science Center of Xi’an Jiaotong University, Xi’an 710061, China
SHI Yan
Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
SHEN Bao-hua
Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
ObjectiveTo analyze the characteristics of diphenidol poisoning cases and to provide clues and technical means for the identification of such cases.MethodsBiological samples of 9 deaths caused by diphenidol poisoning were detected by ultra-high performance liquid chromatography-tandem mass spectrometry （UPLC-MS/MS）, and the characteristics of these cases were analyzed retrospectively.ResultsMost of the deaths caused by diphenidol poisoning were young females. The dosage was between 60 and 300 tablets, and the mass concentration of diphenidol in the postmortem blood ranged from 0.87 to 99.00 μg/mL. There was no correlation between the dosage and the concentration of diphenidol in the blood.ConclusionDiphenidol poisoning has the characteristics of high concealment and lethality. More attention should be paid to suicide cases, and diphenidol should be recommended as a routine detection item to avoid missing detection.
