A study to predict fracture risk using bone mineral density and FRAX score in patients on chronic maintenance haemodialysis

Abstract

Introduction: Disturbances in mineral and bone metabolism are prevalent in chronic kidney disease (CKD) and are important causes of morbidity also their diagnosis often delayed and require a spectrum of investigations. The current study attempts to predict and correlate, the fracture risk using simple tools like BMD and FRAX (Fracture Risk Assessment Tool) score in CKD patients. Methods: A cross-sectional study among 50 CKD patients age more that 40 years attending OPD (Out Patient Department) at a tertiary care Hospital in north India. Results: There is a negative correlation between BMD (NOF) and FRAX score for hip fracture risk and major osteoporotic fracture risk. Conclusion: The 10-year fracture risk in these patients, as predicted by FRAX score using FRAX (Indian) calculator, was significantly higher in CKD patients. Recommendation: FRAX can be useful tool for early screening of fracture risk in such situations for timely interventions.

Keywords

• ckd
• frax
• fracture risk
• haemodialysis