Coumarin Triazoles as Potential Antimicrobial Agents
Siddappa A. Patil,
Aravind R. Nesaragi,
Raúl R. Rodríguez-Berrios,
Sydney M. Hampton,
Alejandro Bugarin,
Shivaputra A. Patil
Affiliations
Siddappa A. Patil
Centre for Nano and Material Sciences, Jain University, Jain Global Campus, Bangalore 562112, Karnataka, India
Aravind R. Nesaragi
Centre for Nano and Material Sciences, Jain University, Jain Global Campus, Bangalore 562112, Karnataka, India
Raúl R. Rodríguez-Berrios
Department of Chemistry, University of Puerto Rico, Rio Piedras Campus, P.O. Box 23346, San Juan 00931-3346, Puerto Rico
Sydney M. Hampton
Department of Chemistry and Physics, Florida Gulf Coast University, 10501 FGCU Boulevard South, Fort Myers, FL 33965, USA
Alejandro Bugarin
Department of Chemistry and Physics, Florida Gulf Coast University, 10501 FGCU Boulevard South, Fort Myers, FL 33965, USA
Shivaputra A. Patil
Pharmaceutical Sciences Department, College of Pharmacy, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA
Currently, in hospitals and community health centers, microbial infections are highly common diseases and are a leading cause of death worldwide. Antibiotics are generally used to fight microbial infections; however, because of the abuse of antibiotics, microbes have become increasingly more resistant to most of them. Therefore, medicinal chemists are constantly searching for new or improved alternatives to combat microbial infections. Coumarin triazole derivatives displayed a variety of therapeutic applications, such as antimicrobial, antioxidant, and anticancer activities. This review summarizes the advances of coumarin triazole derivatives as potential antimicrobial agents covering articles published from 2006 to 2022.
