Nature Communications (Jul 2022)
Biomarkers of nanomaterials hazard from multi-layer data
- Vittorio Fortino,
- Pia Anneli Sofia Kinaret,
- Michele Fratello,
- Angela Serra,
- Laura Aliisa Saarimäki,
- Audrey Gallud,
- Govind Gupta,
- Gerard Vales,
- Manuel Correia,
- Omid Rasool,
- Jimmy Ytterberg,
- Marco Monopoli,
- Tiina Skoog,
- Peter Ritchie,
- Sergio Moya,
- Socorro Vázquez-Campos,
- Richard Handy,
- Roland Grafström,
- Lang Tran,
- Roman Zubarev,
- Riitta Lahesmaa,
- Kenneth Dawson,
- Katrin Loeschner,
- Erik Husfeldt Larsen,
- Fritz Krombach,
- Hannu Norppa,
- Juha Kere,
- Kai Savolainen,
- Harri Alenius,
- Bengt Fadeel,
- Dario Greco
Affiliations
- Vittorio Fortino
- Institute of Biomedicine, University of Eastern Finland
- Pia Anneli Sofia Kinaret
- Faculty of Medicine and Health Technology, Tampere University
- Michele Fratello
- Faculty of Medicine and Health Technology, Tampere University
- Angela Serra
- Faculty of Medicine and Health Technology, Tampere University
- Laura Aliisa Saarimäki
- Faculty of Medicine and Health Technology, Tampere University
- Audrey Gallud
- Institute of Environmental Medicine, Karolinska Institutet
- Govind Gupta
- Institute of Environmental Medicine, Karolinska Institutet
- Gerard Vales
- Finnish Institute of Occupational Health
- Manuel Correia
- National Food Institute, Technical University of Denmark
- Omid Rasool
- Turku Bioscience Centre, University of Turku, and Åbo Akademi University
- Jimmy Ytterberg
- Department of Medical Biochemistry and Biophysics, Karolinska Institutet
- Marco Monopoli
- Department of Pharmaceutical and Medicinal Chemistry, Royal College of Surgeons in Ireland
- Tiina Skoog
- Department of Biosciences and Nutrition, Karolinska Institutet
- Peter Ritchie
- Institute of Occupational Medicine
- Sergio Moya
- Soft Matter Nanotechnology Laboratory, CIC biomaGUNE
- Socorro Vázquez-Campos
- Leitat Technological Center
- Richard Handy
- School of Biological and Marine Sciences, University of Plymouth
- Roland Grafström
- Institute of Environmental Medicine, Karolinska Institutet
- Lang Tran
- Institute of Occupational Medicine
- Roman Zubarev
- Department of Medical Biochemistry and Biophysics, Karolinska Institutet
- Riitta Lahesmaa
- Turku Bioscience Centre, University of Turku, and Åbo Akademi University
- Kenneth Dawson
- Centre for BioNano Interactions, School of Chemistry and Chemical Biology, University College Dublin
- Katrin Loeschner
- National Food Institute, Technical University of Denmark
- Erik Husfeldt Larsen
- National Food Institute, Technical University of Denmark
- Fritz Krombach
- Walter Brendel Centre of Experimental Medicine, Ludwig-Maximilians-Universität München
- Hannu Norppa
- Finnish Institute of Occupational Health
- Juha Kere
- Department of Biosciences and Nutrition, Karolinska Institutet
- Kai Savolainen
- Finnish Institute of Occupational Health
- Harri Alenius
- Institute of Environmental Medicine, Karolinska Institutet
- Bengt Fadeel
- Institute of Environmental Medicine, Karolinska Institutet
- Dario Greco
- Faculty of Medicine and Health Technology, Tampere University
- DOI
- https://doi.org/10.1038/s41467-022-31609-5
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 10
Abstract
Nanomaterials have a range of potential applications, however, toxicity remains a concern, limiting application and requiring extensive testing. Here, the authors report on a predictive framework made using a range of tests linking materials properties with toxicity, allowing the prediction of toxicity from physiochemical and biological properties.
