SYNTHETIC TRANSFORMATIONS OF ENT-KAURENOIC ACID

Abstract

This paper presents a review on kaurane diterpenes, covering various aspects of chemical and microbiological transformations of native ent-kaurenoic acid, namely, its reactions via COOH groups, double bonds and rearrangements of the carbon skeleton that lead to a wide range of natural and synthetic derivatives with potential biologic activities and can present convenient synthons for the syntheses of other native ent-kauranes.

Keywords

• diterpenes
• ent-kaur-16-en-19-oic acid
• synthesis