Nature Communications (Apr 2020)

Re-definition of claudin-low as a breast cancer phenotype

  • Christian Fougner,
  • Helga Bergholtz,
  • Jens Henrik Norum,
  • Therese Sørlie

DOI
https://doi.org/10.1038/s41467-020-15574-5
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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In breast cancer, the claudin-low breast cancer subtype is remarkably diverse. Here, the authors propose that claudin-low is not a classical intrinsic breast cancer subtype, but rather a complex additional phenotype that can occur across intrinsic subtypes.