EFFECTS OF VASCULAR BURDEN ON COGNITION ARE MEDIATED BY ATROPHY, AMYLOID, AND GLUCOSE METABOLISM: A MULTI-CENTRE MIXED COHORT OF SMALL VESSEL DISEASE AND ALZHEIMER'S PATHOLOGY

• Julie Ottoy, LC Campbell,
• Miracle Ozzoude, LC Campbell,
• Katherine Zukotynski, LC Campbell,
• Sabrina Adamo, LC Campbell,
• Christopher Scott, LC Campbell,
• Vincent Gaudet,
• Joel Ramirez, LC Campbell,
• Walter Swardfager,
• Hugo Cogo-Moreira, LC Campbell,
• Benjamin Lam, LC Campbell,
• Aparna Bhan, LC Campbell,
• Parisa Mojiri, LC Campbell,
• Min Su Kang,
• Jennifer Rabin, LC Campbell,
• Alex Kiss,
• Stephen Strother,
• Christian Bocti,
• Michael Borrie,
• Howard Chertkow,
• Richard Frayne,
• Robin Hsiung,
• Robert Laforce, Jr.,
• Michael D. Noseworthy,
• Frank S. Prato,
• Demetrios J. Sahlas,
• Eric E. Smith,
• Phillip H. Kuo,
• Vesna Sossi,
• Alexander Thiel,
• Jean-Paul Soucy,
• Jean-Claude Tardif,
• Sandra E. Black, LC Campbell,
• Maged Goubran, LC Campbell

Affiliations

Julie Ottoy, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Miracle Ozzoude, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Katherine Zukotynski, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada; Departments of Medicine and Radiology, McMaster University, Hamilton, ON, Canada

Sabrina Adamo, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Christopher Scott, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Vincent Gaudet

Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, ON, Canada

Joel Ramirez, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Walter Swardfager

Department of Pharmacology & Toxicology, University of Toronto, ON, Canada

Hugo Cogo-Moreira, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Benjamin Lam, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Aparna Bhan, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Parisa Mojiri, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Min Su Kang

Montreal Neurological Institute, McGill University, Montreal, QC, Canada

Jennifer Rabin, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada; Departments of Medicine and Radiology, McMaster University, Hamilton, ON, Canada

Alex Kiss

Department of Research Design and Biostatistics, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

Stephen Strother

The Rotman Research Institute Baycrest, University of Toronto, Toronto, ON, Canada

Christian Bocti

Département de médecine, Université de Sherbrooke, Sherbrooke, QC, Canada

Michael Borrie

Lawson Health Research Institute, Western University, London, ON, Canada

Howard Chertkow

Jewish General Hospital, McGill University, Montreal, QC, Canada

Richard Frayne

Departments of Radiology and Clinical Neuroscience, University of Calgary, Calgary, AB, Canada

Robin Hsiung

Physics and Astronomy Department and DM Center for Brain Health, University of British Columbia, Vancouver, BC, Canada

Robert Laforce, Jr.

Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques, Université Laval, Québec, QC, Canada

Michael D. Noseworthy

Department of Electrical and Computer Engineering, McMaster University, Hamilton, ON, Canada

Frank S. Prato

Lawson Health Research Institute, Western University, London, ON, Canada

Demetrios J. Sahlas

Department of Medicine, McMaster University, Hamilton, ON, Canada

Eric E. Smith

Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada

Phillip H. Kuo

Department of Medical Imaging, Medicine, and Biomedical Engineering, University of Arizona, Tucson, AZ, USA

Vesna Sossi

Physics and Astronomy Department and DM Center for Brain Health, University of British Columbia, Vancouver, BC, Canada

Alexander Thiel

Jewish General Hospital, McGill University, Montreal, QC, Canada

Jean-Paul Soucy

Montreal Neurological Institute, McGill University, Montreal, QC, Canada

Jean-Claude Tardif

Montreal Heart Institute, Université de Montréal, Montreal, QC, Canada

Sandra E. Black, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada; Department of Medicine (Division of Neurology), University of Toronto, Toronto, ON, Canada

Maged Goubran, LC Campbell

Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada