A pluripotent stem cell-based model for post-implantation human amniotic sac development

Yue Shao; Kenichiro Taniguchi; Ryan F. Townshend; Toshio Miki; Deborah L. Gumucio; Jianping Fu

doi:10.1038/s41467-017-00236-w

Nature Communications (Aug 2017)

A pluripotent stem cell-based model for post-implantation human amniotic sac development

Yue Shao,
Kenichiro Taniguchi,
Ryan F. Townshend,
Toshio Miki,
Deborah L. Gumucio,
Jianping Fu

Affiliations

Yue Shao: Department of Mechanical Engineering, University of Michigan
Kenichiro Taniguchi: Department of Cell and Developmental Biology, University of Michigan Medical School
Ryan F. Townshend: Department of Cell and Developmental Biology, University of Michigan Medical School
Toshio Miki: Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California
Deborah L. Gumucio: Department of Cell and Developmental Biology, University of Michigan Medical School
Jianping Fu: Department of Mechanical Engineering, University of Michigan

DOI: https://doi.org/10.1038/s41467-017-00236-w
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 15

Abstract

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Early in human embryonic development, it is unclear how amniotic sac formation is regulated. Here, the authors use a human pluripotent stem cell-based model, termed the post-implantation amniotic sac embryoid, to recapitulate early embryogenic events of human amniotic sac development.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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