Journal of King Saud University: Science (Dec 2024)
Non-ablative laser skin rejuvenation by targeting indigenous chromophores
Abstract
Three pulsed laser systems: 980 nm semiconductor diode laser, 1064 nm Nd: YAG laser and long pulse- fractional 2940 nm pulsed Er: YAG were used to treat some non-ablative skin rejuvenation applications. These three wavelengths can target the three main indigenous chromophores (melanin, hemoglobin and water) of the skin to treat different skin disorders. The efficacy of these lasers was assessed in the treatment of age spots, enlarged veins and wrinkles. The chromophore type and location of a specific disorder was taken into consideration when working out, in advance, the required laser fluence. The absorption of laser photons and the reabsorbed photon scattering were calculated and used to work out the temperature rise in the targeted tissue. The results indicated very good outcome of age spots with 980 nm laser, excellent clearance of the varicose veins with the use of 1064 nm laser and very good smoothing of fine lines wrinkles on forehead. Advances may involve conducting wavelengths or developing customizable protocols for different skin types. Long-term studies on patient outcomes to help establish standardized protocols and improve efficacy in clinical uses.