Nature Communications (Apr 2020)

Artifact-free and high-temporal-resolution in vivo opto-electrophysiology with microLED optoelectrodes

  • Kanghwan Kim,
  • Mihály Vöröslakos,
  • John P. Seymour,
  • Kensall D. Wise,
  • György Buzsáki,
  • Euisik Yoon

DOI
https://doi.org/10.1038/s41467-020-15769-w
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Artifact-free opto-electrophysiology is key for precise modulation and monitoring of individual neurons at high spatio-temporal resolution. The authors present a method for eliminating stimulation artifacts in high-density micro-LED optoelectrodes for accurate functional mapping of local circuits.