Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma

Joseph Lopez, MD, MBA; Nancy Qin, BA; Robbie Woods, MD; Marjorie Golden, MFA, CDT; Harrison Spatz, DMD, MS; Jatin Shah, MD; Leonard H. Wexler, MD; Joseph Randazzo, DDS; Suzanne L. Wolden, MD; David H. Abramson, MD

doi:10.1097/GOX.0000000000004581

Plastic and Reconstructive Surgery, Global Open (Oct 2022)

Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma

Joseph Lopez, MD, MBA,
Nancy Qin, BA,
Robbie Woods, MD,
Marjorie Golden, MFA, CDT,
Harrison Spatz, DMD, MS,
Jatin Shah, MD,
Leonard H. Wexler, MD,
Joseph Randazzo, DDS,
Suzanne L. Wolden, MD,
David H. Abramson, MD

Affiliations

Joseph Lopez, MD, MBA: From the * Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.
Nancy Qin, BA: From the * Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.
Robbie Woods, MD: From the * Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.
Marjorie Golden, MFA, CDT: † Department of Surgery, Dental Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.
Harrison Spatz, DMD, MS: † Department of Surgery, Dental Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.
Jatin Shah, MD: From the * Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.
Leonard H. Wexler, MD: ‡ Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, N.Y.
Joseph Randazzo, DDS: † Department of Surgery, Dental Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.
Suzanne L. Wolden, MD: § Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, N.Y.
David H. Abramson, MD: ¶ Department of Surgery, Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.

DOI: https://doi.org/10.1097/GOX.0000000000004581
Journal volume & issue: Vol. 10, no. 10
p. e4581

Abstract

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SUMMARY. A 20-month-old boy presented with biopsy-proven recurrent alveolar rhabdomyosarcoma without metastasis. He was previously treated with multiagent chemotherapy and external beam irradiation showing a complete response. Upon relapse, he was treated with chemotherapy, orbital exenteration, and brachytherapy. Customized, intraoperative brachytherapy has potential to limit the sequelae associated with radiation adjuvant therapy.

Published in Plastic and Reconstructive Surgery, Global Open

ISSN: 2169-7574 (Online)
Publisher: Wolters Kluwer
Country of publisher: United States
LCC subjects: Medicine: Surgery
Website: http://www.prsgo.com

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