Frontiers in Allergy (Apr 2024)

New-onset egg allergy in an adult: A case report

  • Michimasa Fujiwara,
  • Takashi Kimura,
  • Junya Ohira,
  • Motohiro Inotani,
  • Tomoko Sakane,
  • Mizue Iwase,
  • Sadanori Yamashita,
  • Tooru Araki

DOI
https://doi.org/10.3389/falgy.2024.1395807
Journal volume & issue
Vol. 5

Abstract

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Most adult cases of hen's egg allergy are carried over from childhood, and new-onset adult cases are rare. Such cases may result from cross-reactivity or sensitization by inhalation. Here we present a rare case of adult-onset egg allergy due to monosensitization to ovalbumin (Gal d 2) with an unclear sensitization pathway. A 27-year-old woman developed recurrent gastrointestinal symptoms after ingestion of raw and under-cooked eggs. She had never suffered from atopic dermatitis or food allergies. She had never kept birds as pets and had no history of exposure to egg allergens. Prick to prick testing was positive only with raw egg white. Specific IgE testing revealed monosensitization to Gal d 2. She was advised to avoid raw and undercooked eggs and her symptoms resolved. In the management of adult-onset egg allergy, evaluation of allergen components will lead to appropriate elimination guidelines, and investigation of sensitization pathways may help identify the cause of this disease.

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