The discovery of beta-blockers

Abstract

The introduction of β-adrenergic-blocking drugs in the early 1960s represented a major advance in therapeutics. Their use highlighted the importance of the sympathetic nervous system. This article briefly highlights some of the steps in their development.

Keywords

• Bacteriologist
• Carvedilol Prospective Randomized Cumulative Survival Study
• immunologist
• Metoprolol Randomized Intervention Trial in Congestive Heart Failure