Nutraceutic Potential of Bioactive Compounds of <i>Eugenia dysenterica</i> DC in Metabolic Alterations
Lidiani Figueiredo Santana,
Sandramara Sasso,
Diana Figueiredo Santana Aquino,
Karine de Cássia Freitas,
Rita de Cássia Avellaneda Guimarães,
Arnildo Pott,
Valter Aragão do Nascimento,
Danielle Bogo,
Patrícia de Oliveira Figueiredo,
Priscila Aiko Hiane
Affiliations
Lidiani Figueiredo Santana
Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79070-900, Brazil
Sandramara Sasso
Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79070-900, Brazil
Diana Figueiredo Santana Aquino
Higher Level Technician, Personnel Development Division, State University of Mato Grosso do Sul—UEMS, Dourados 79804-970, Brazil
Karine de Cássia Freitas
Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79070-900, Brazil
Rita de Cássia Avellaneda Guimarães
Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79070-900, Brazil
Arnildo Pott
Institute of Biosciences, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79079-900, Brazil
Valter Aragão do Nascimento
Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79070-900, Brazil
Danielle Bogo
Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79070-900, Brazil
Patrícia de Oliveira Figueiredo
Laboratory Pronabio (Bioactive Natural Products)-Chemistry Institute, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79074-460, Brazil
Priscila Aiko Hiane
Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul—UFMS, Campo Grande 79070-900, Brazil
The fruit and leaves of Eugenia dysenterica DC., locally known as cagaita, are rich in antioxidant glycosylated quercetin derivatives and phenolic compounds that have beneficial effects on diabetes mellitus, hypertension and general inflammation. We conducted a literature search to investigate the nutraceutical potentials of these phenolic compounds for treating obesity, diabetes mellitus and intestinal inflammatory disease. The phenolic compounds in E. dysenterica have demonstrated effects on carbohydrate metabolism, which can prevent the development of these chronic diseases and reduce LDL (low-density lipoprotein) cholesterol and hypertension. E. dysenterica also improves intestinal motility and microbiota and protects gastric mucosa, thereby preventing inflammation. However, studies are necessary to identify the mechanism by which E. dysenterica nutraceutical compounds act on such pathological processes to support future research.