Correlation of Brachial Cuff Oscillometric Device Based Central Haemodynamic Indices with Syntax Score in Patients with Coronary Artery Disease

Abstract

Introduction: Early recognition of atherosclerosis is important, considering the epidemic proportion of Cardiovascular Disease (CVD) across the world. Non invasive methods of estimation of central blood pressure and other parameters help in early recognition of atherosclerosis. Aim: To measure the Central Haemodynamic Indices (CHIs) by a non-invasive brachial cuff based oscillometric methodCentral Blood Pressure (CBP), Central Pulse Pressure (CPP), Pulse Pressure Amplification (PPA), Augmentation Index (AIx), Augmentation index @ 75, Reflection coefficient, Pulse Wave Velocity (PWV), Total Peripheral Resistance (TPR). To evaluate the Angiographic severity of patients by Syntax Score (SS) and correlate with the CHIs. Materials and Methods: The present study was a hospital based observational study. A total of 120 patients presenting with symptoms suggestive of Coronary Artery Disease (CAD) with age >18 years and those willing to undergo conventional coronary angiography were included. Patients with cardiogenic shock, Chronic kidney disease (eGFR 23) according to ROC curves are 9.5 mmHg, 23.7, 9.35 m/sec respectively. Conclusion: CHIs assessed noninvasively have a significant role in the clinical evaluation and an incremental value in the risk stratification of the CAD patients.

Keywords

• augmentation index
• central blood pressure
• pulse pressure amplification
• total peripheral resistance