In order to evaluate and access the best conditions to cultivate saffron in Tabriz, an experiment was conducted at the Agricultural Research Station of the University of Tabriz (Khalatpooshan), in a factorial experiment based on randomized complete block design and three replications. The treatments included two ecotypes of saffron in 4 levels of mother corm weight (3.1- 5, 5.1- 7, 7.1- 9 and more than 9 g) and two planting methods (row and mass). The results showed that corm weight and planting method had significant effects on the number and weight of replacement corms. But there was no significant effect on the different ecotypes. Among the experimental treatments, corms with 7.1- 9 g weight lead to the highest total corm number (342.65 corm.m-2) and corm yield (892.9 g.m-2) and the yield of flowers and stigma of saffron. It seems that for production of larger replacement corms and increased flowering yield, we need to culture large maternal corms. In addition, we observed the best economical yield that is determined by amount of stigma, in row planting method. The results showed that row planting method leads to a higher amount and yield of replacement corm production in comparison to mass planting method. As a result, producing corms with high weight followed by increasing of flower yield requires the use of large maternal corms for cultivation and row planting method.