Dataset on the role of endoglin expression on melanin production in murine melanoma and on the influence of melanin on optical imaging
Felista L. Tansi,
Ronny Rüger,
Ansgar M. Kollmeier,
Markus Rabenhold,
Frank Steiniger,
Roland E. Kontermann,
Ulf K. Teichgraeber,
Alfred Fahr,
Ingrid Hilger
Affiliations
Felista L. Tansi
Institute of Diagnostic and Interventional Radiology, Experimental Radiology, Jena University Hospital, Am klinikum 1, 07747 Jena, Germany; Corresponding author.
Ronny Rüger
Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena, Lessingstrasse 8, 07743 Jena, Germany
Ansgar M. Kollmeier
Institute of Diagnostic and Interventional Radiology, Experimental Radiology, Jena University Hospital, Am klinikum 1, 07747 Jena, Germany
Markus Rabenhold
Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena, Lessingstrasse 8, 07743 Jena, Germany
Frank Steiniger
Center for Electron Microscopy, Jena University Hospital, Ziegelmuehlenweg 1, 07743 Jena, Germany
Roland E. Kontermann
Institute of Cell Biology and Immunology, University Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
Ulf K. Teichgraeber
Institute of Diagnostic and Interventional Radiology, Experimental Radiology, Jena University Hospital, Am klinikum 1, 07747 Jena, Germany
Alfred Fahr
Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena, Lessingstrasse 8, 07743 Jena, Germany
Ingrid Hilger
Institute of Diagnostic and Interventional Radiology, Experimental Radiology, Jena University Hospital, Am klinikum 1, 07747 Jena, Germany
The underlying data demonstrates that the expression of endoglin in murine melanoma cells influences melanin production in the cells. Also, the data shows that melanin production is further increased when the cells are subcutaneously implanted in mice models and that the high melanin production prevents detection of the cells by fluorescence imaging. The processed data presented herein is related to a research article by Tansi et al. (2018) entitled “Endoglin based in vivo near-infrared fluorescence imaging of tumor models in mice using activatable liposomes”.
