Polymers (Feb 2022)

Bioactive Graphene Quantum Dots Based Polymer Composite for Biomedical Applications

  • Seyyed Mojtaba Mousavi,
  • Seyyed Alireza Hashemi,
  • Masoomeh Yari Kalashgrani,
  • Navid Omidifar,
  • Sonia Bahrani,
  • Neralla Vijayakameswara Rao,
  • Aziz Babapoor,
  • Ahmad Gholami,
  • Wei-Hung Chiang

DOI
https://doi.org/10.3390/polym14030617
Journal volume & issue
Vol. 14, no. 3
p. 617

Abstract

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Today, nanomedicine seeks to develop new polymer composites to overcome current problems in diagnosing and treating common diseases, especially cancer. To achieve this goal, research on polymer composites has expanded so that, in recent years, interdisciplinary collaborations between scientists have been expanding day by day. The synthesis and applications of bioactive GQD-based polymer composites have been investigated in medicine and biomedicine. Bioactive GQD-based polymer composites have a special role as drug delivery carriers. Bioactive GQDs are one of the newcomers to the list of carbon-based nanomaterials. In addition, the antibacterial and anti-diabetic potentials of bioactive GQDs are already known. Due to their highly specific surface properties, π-π aggregation, and hydrophobic interactions, bioactive GQD-based polymer composites have a high drug loading capacity, and, in case of proper correction, can be used as an excellent option for the release of anticancer drugs, gene carriers, biosensors, bioimaging, antibacterial applications, cell culture, and tissue engineering. In this paper, we summarize recent advances in using bioactive GQD-based polymer composites in drug delivery, gene delivery, thermal therapy, thermodynamic therapy, bioimaging, tissue engineering, bioactive GQD synthesis, and GQD green resuscitation, in addition to examining GQD-based polymer composites.

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