Communications Biology (Dec 2022)

Alternative splicing and genetic variation of mhc-e: implications for rhesus cytomegalovirus-based vaccines

  • Hayden Brochu,
  • Ruihan Wang,
  • Tammy Tollison,
  • Chul-Woo Pyo,
  • Alexander Thomas,
  • Elizabeth Tseng,
  • Lynn Law,
  • Louis J. Picker,
  • Michael Gale,
  • Daniel E. Geraghty,
  • Xinxia Peng

DOI
https://doi.org/10.1038/s42003-022-04344-2
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 13

Abstract

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The alternative splicing and genetic variations across the whole MHC-E locus of Rhesus Macaques (Mamu-E) are analysed, which provides a foundation for more comprehensive research of Mamu-E and informs translational research of CMV-based vaccines.