Global Pediatrics (Mar 2025)
Turkish Neonatal Society position paper for stem cell therapy in neonates
- Merih Cetinkaya,
- Esin Koc,
- Betul Acunas,
- Mete Akisu,
- Saadet Arsan,
- Fuat Emre Canpolat,
- Dilek Dilli,
- Zeynep Ince,
- Nilgun Koksal,
- Abdullah Kumral,
- Eren Ozek,
- Hasan Ozkan,
- Ayse Korkmaz Toygar,
- Sule Yigit,
- Aysegul Zenciroglu,
- Mehmet Vural
Affiliations
- Merih Cetinkaya
- Division of Neonatology, Department of Pediatrics, Health Sciences University, Basaksehir Cam Sakura City Hospital, Istanbul, Turkiye; Corresponding author at: Basaksehir Cam and Sakura City Hospital, Dept. of Pediatrics, Division of Neonatology, Başakşehir Mahallesi G-434 Caddesi No: 2L, 34480, Başakşehir, Istanbul, Turkiye.
- Esin Koc
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Gazi University, Ankara, Turkiye; European Pediatric Association, Union of National European Pediatric Societies and Associations, Berlin, Germany
- Betul Acunas
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Trakya University, Edirne, Turkiye
- Mete Akisu
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Ege University, Izmir, Turkiye
- Saadet Arsan
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Ankara University, Ankara, Turkiye
- Fuat Emre Canpolat
- Division of Neonatology, Department of Pediatrics, Health Sciences University, Ankara Bilkent City Hospital, Ankara, Turkiye
- Dilek Dilli
- Division of Neonatology, Department of Pediatrics, Health Sciences University, Ankara Etlik City Hospital, Ankara, Turkiye
- Zeynep Ince
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Istanbul University, Istanbul, Turkiye
- Nilgun Koksal
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Bursa Uludag University, Bursa, Turkiye
- Abdullah Kumral
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Marmara University, Istanbul, Turkiye
- Eren Ozek
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Marmara University, Istanbul, Turkiye
- Hasan Ozkan
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkiye
- Ayse Korkmaz Toygar
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Turkiye
- Sule Yigit
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkiye
- Aysegul Zenciroglu
- Division of Neonatology, Department of Pediatrics, Health Sciences University, Ankara Etlik Zubeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkiye
- Mehmet Vural
- Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Istanbul Cerrahpasa University, Istanbul, Turkiye
- Journal volume & issue
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Vol. 11
p. 100239
Abstract
Stem cell (SC) therapy has been proposed as a promising therapeutic modality in neonatology, especially for prevention and/or treatment of several interactable diseases such as bronchopulmonary dysplasia, intraventricular hemorrhage, hypoxic-ischemic encephalopathy and others. However, there are several uncertainities in terms of indications, timing, dosage, and safety of SC therapy for routine clinical use in neonates. Herein, a group of Turkish Neonatal Society members evaluated the systematic reviews, meta-analyses, clinical and experimental studies and also case-reports in the literature about the usage of SC therapy in neonatal diseases.
