A Point Prevalence Survey of Antimicrobial Use in Second-Level Mexican Hospitals: A Multicenter Study
German Alberto Venegas-Esquivel,
María Guadalupe Berumen-Lechuga,
Carlos José Molina-Pérez,
Rodolfo Norberto Jimenez-Juarez,
Enna Guadalupe Villanueva-Cabrera,
David Vargas-González,
Gonzalo Santos-González,
Rebeca Pamela Velázquez Pérez,
Mariana Hernández Navarrete,
Celene Corral-Rico,
Natali Robles-Ordoñez,
Juan Manuel Lara-Hernández,
Helen’s Irais Sánchez Mendoza
Affiliations
German Alberto Venegas-Esquivel
Pediatric Department, Hospital de Ginecología y Obstetricia 221, Instituto Mexicano del Seguro Social (IMSS), Toluca 50000, Mexico
María Guadalupe Berumen-Lechuga
Medical Research Coordination, Órgano de Operación Administrativa Desconcentrada Regional Mexico Poniente, Instituto Mexicano del Seguro Social (IMSS), Toluca 50000, Mexico
Carlos José Molina-Pérez
Health Research Division, Unidad Médica de Alta Especialidad Hospitalde Ginecología y Obstetricia No. 4, Instituto Mexicano del Seguro Social (IMSS), Mexico 01090, Mexico
Rodolfo Norberto Jimenez-Juarez
Infectious Diseases Departament, Federico Gómez Children’s Hospital of Mexico, Mexico City 06720, Mexico
Enna Guadalupe Villanueva-Cabrera
Resident Emergency Departament, Hospital General Regional No. 251, Instituto Mexicano del Seguro Social (IMSS), Metepec 52148, Mexico
David Vargas-González
Resident Emergency Departament, Hospital General de Zona número 194, Instituto Mexicano del Seguro Social (IMSS), El Molinito 53000, Mexico
Gonzalo Santos-González
Resident General Surgery Department, Hospital General Regional 251, Instituto Mexicano del Seguro Social, Metepec 52104, Mexico
Rebeca Pamela Velázquez Pérez
Social Service Intern, Education and Research Deparment, Hospital General de Zona 252, Instituto Mexicano del Seguro Social (IMSS), Atlacomulco 50450, Mexico
Mariana Hernández Navarrete
Social Service Intern, Education and Research Deparment, Hospital General de Zona 252, Instituto Mexicano del Seguro Social (IMSS), Atlacomulco 50450, Mexico
Celene Corral-Rico
Neonatology Departament, Hospital para el Nino, Instituto Materno Infantil del Estado de Mexico, Toluca 50170, Mexico
Natali Robles-Ordoñez
Infectious Diseases Department, Hospital para el Nino, Instituto Materno Infantil del Estado de Mexico, Toluca 50170, Mexico
Juan Manuel Lara-Hernández
Intensive Care Department, Hospital de Ginecología y Obstetricia 221, Instituto Mexicano del Seguro Social (IMSS), Toluca 50000, Mexico
Helen’s Irais Sánchez Mendoza
Medical School, Autonomous University of the State of Mexico, Toluca 50180, Mexico
In 2018, the WHO published a methodology for conducting a point prevalence survey (PPS) of antibiotic use in hospitals. The aim of this study is to report the use of antibiotics in six second-level hospitals in Mexico using this methodology. Methods: A multicenter cross-sectional study based on the 2021–2023 adaptation for Latin American hospitals was conducted in internal medicine, surgery, intensive care unit (ICU), obstetrics and gynecology and pediatrics departments of the IMSS in the western region of the state of Mexico. Results: The overall prevalence of antibiotic use was 61%; the services with the highest prevalence of prescription were general surgery (79%) and the ICU (78%). A total of 846 patients were surveyed; there were no differences in antibiotic use or non-use in terms of gender, surgical procedure and invasive devices, but there were differences in median age and comorbidities. Adherence to guidelines was 53.9%. The three main antibiotics used were third-generation cephalosporins (28%), carbapenems (13%) and glycopeptides (9%); for the type of indication, for CAI and prophylaxis, the rates of use of third-generation cephalosporins were 29.2% and 44.5%, respectively, while for healthcare-associated infections, carbapenems were used (23.9%). By AWaRe group, the watch group was predominant for all types (63.9%), for prophylaxis it was the access group (39.3%), and for HAIs it was the reserve group (4.9%).
