Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs

Christopher D. Scharer; Benjamin G. Barwick; Muyao Guo; Alexander P. R. Bally; Jeremy M. Boss

doi:10.1038/s41467-018-04125-8

Nature Communications (Apr 2018)

Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs

Christopher D. Scharer,
Benjamin G. Barwick,
Muyao Guo,
Alexander P. R. Bally,
Jeremy M. Boss

Affiliations

Christopher D. Scharer: Department of Microbiology and Immunology, Emory University
Benjamin G. Barwick: Department of Microbiology and Immunology, Emory University
Muyao Guo: Department of Microbiology and Immunology, Emory University
Alexander P. R. Bally: Department of Microbiology and Immunology, Emory University
Jeremy M. Boss: Department of Microbiology and Immunology, Emory University

DOI: https://doi.org/10.1038/s41467-018-04125-8
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 14

Abstract

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During B cell differentiation, the role of different genomic loci in transcriptional and epigenetic regulation in vivo is not well defined. Here the authors use an in vivo B cell differentiation model to map cellular division-dependent cis-regulatory element road map with ATAC-seq.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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