Communications Biology (Feb 2021)
Spermidine-induced recovery of human dermal structure and barrier function by skin microbiome
- Gihyeon Kim,
- Misun Kim,
- Minji Kim,
- Changho Park,
- Youngmin Yoon,
- Doo-Hyeon Lim,
- Hyeonju Yeo,
- Seunghyun Kang,
- Yeong-Geun Lee,
- Nam-In Beak,
- Jongsung Lee,
- Sujeong Kim,
- Jee Young Kwon,
- Won Woo Choi,
- Charles Lee,
- Kyoung Wan Yoon,
- Hansoo Park,
- Dong-Geol Lee
Affiliations
- Gihyeon Kim
- Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST)
- Misun Kim
- R&I Center, COSMAX BTI
- Minji Kim
- R&I Center, COSMAX BTI
- Changho Park
- Genome and Company
- Youngmin Yoon
- Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST)
- Doo-Hyeon Lim
- R&I Center, COSMAX BTI
- Hyeonju Yeo
- R&I Center, COSMAX BTI
- Seunghyun Kang
- R&I Center, COSMAX BTI
- Yeong-Geun Lee
- Graduate School of Biotechnology and Department of Oriental Medicine Biotechnology, Kyung Hee University
- Nam-In Beak
- Graduate School of Biotechnology and Department of Oriental Medicine Biotechnology, Kyung Hee University
- Jongsung Lee
- Dermatology Laboratory, Department of Integrative Biotechnology & Biocosmetics Research Center, College of Biotechnology and Bioengineering, Sungkyunkwan University
- Sujeong Kim
- Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST)
- Jee Young Kwon
- The Jackson Laboratory for Genomic Medicine
- Won Woo Choi
- Wells Dermatology Clinic
- Charles Lee
- The Jackson Laboratory for Genomic Medicine
- Kyoung Wan Yoon
- Genome and Company
- Hansoo Park
- Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST)
- Dong-Geol Lee
- R&I Center, COSMAX BTI
- DOI
- https://doi.org/10.1038/s42003-020-01619-4
- Journal volume & issue
-
Vol. 4,
no. 1
pp. 1 – 11
Abstract
Kim et al. show that several Streptococcus species improve the structure and barrier function of human skin. They find that Streptococcus-secreted spermidine accelerates the recovery of skin structure and barrier function by increasing collagen and lipid synthesis in aged cells. This study suggests the role of skin microbiome for anti-aging.
