Quick determination of Glyphosate and AMPA at sub µg/L in drinking water by direct injection into LC-MS/MS
Vicent Yusà,
Yovana Sanchís,
Pablo Dualde,
Elvira Carbonell,
Clara Coscollà
Affiliations
Vicent Yusà
Public Health Laboratory of Valencia, Av. Cataluña, 21, 46020 Valencia, Spain; Foundation for the Promotion of Health and Biomedical Research of the Valencian Region, FISABIO-Public Health, Av. Catalunya, 21, 46020 Valencia, Spain; Analytical Chemistry Department, University of Valencia, Edifici Jeroni Muñoz, Dr. Moliner 50, 46100 Burjassot, Spain; Corresponding author.
Yovana Sanchís
Public Health Laboratory of Valencia, Av. Cataluña, 21, 46020 Valencia, Spain
Pablo Dualde
Foundation for the Promotion of Health and Biomedical Research of the Valencian Region, FISABIO-Public Health, Av. Catalunya, 21, 46020 Valencia, Spain
Elvira Carbonell
Public Health Laboratory of Valencia, Av. Cataluña, 21, 46020 Valencia, Spain
Clara Coscollà
Public Health Laboratory of Valencia, Av. Cataluña, 21, 46020 Valencia, Spain
A sensitive, simple and quick method for the determination of glyphosate (Gly) and its degradation product, Aminomethyl phosphonic acid (AMPA), in water through ion chromatography coupled to quadrupole-linear ion trap mass spectrometry has been developed. Sample treatment was based on direct injection and acquisition was implemented in both MS2 and MS3 modes. The LoQs of the method were 0.03 µ/L for both Gly-and AMPA. The recoveries were between 91 and 118% and RSD was lower than 15%. The developed methodology was applied on 436 water samples.
