Journal of Functional Foods (Nov 2022)

Biological properties and activities of major royal jelly proteins and their derived peptides

  • Carmen Ioana Mureşan,
  • Daniel Severus Dezmirean,
  • Bianca Dana Marc,
  • Ramona Suharoschi,
  • Oana Lelia Pop,
  • Anja Buttstedt

Journal volume & issue
Vol. 98
p. 105286

Abstract

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Royal jelly (RJ) is a complex beehive product that is important for larval development and queen nutrition in the hive and may also have beneficial effects on human health, according to in vitro and in vivo studies. The main proteins in RJ belong to the Major royal jelly proteins family (MRJPs), representing up to 90% of the total proteins. This narrative review aims to compile the results of studies on MRJPs and their derived peptides to understand their biological effects better, their most important activities being antioxidant, antimicrobial, anti-tumor, hypotensive, hypolipidemic, cell growth promoting, wound healing, anti-aging, neuroprotective, anti-inflammatory and immune-modulatory.

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