Гинекология (Dec 2013)
Evaluation of the hereditary trombophilia forms frequency in infertility patients joining the ART program
Abstract
The analysis of the frequency of detection of polymorphisms of genes associated with the risk of multifactorial disease in patients with infertility who applied to the clinic for the implementation of pregravid preparation before assisted reproductive technologies. We studied gene polymorphisms of platelet fibrinogen receptor, collagen, coagulation factors, F2, 5, 7, 13. The study of the individual parameters of hemostasis deviations from normal variants have been identified. Significantly were significant indicators that reflect gene polymorphism inherited thrombophilia factors 2,7 and platelet fibrinogen receptor. The definition of these parameters would eliminate the risk of thrombosis during hormonal stimulation in patients with infertility.
