Communications Biology (May 2022)

Opening opportunities for K d determination and screening of MHC peptide complexes

  • Janine-Denise Kopicki,
  • Ankur Saikia,
  • Stephan Niebling,
  • Christian Günther,
  • Raghavendra Anjanappa,
  • Maria Garcia-Alai,
  • Sebastian Springer,
  • Charlotte Uetrecht

DOI
https://doi.org/10.1038/s42003-022-03366-0
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 11

Abstract

Read online

The authors present a sensitive and rapid method to determine the binding strength of MHC class 1 peptide complexes using native mass spectrometry.