Journal of Clinical and Diagnostic Research (Nov 2017)
Congenital Adrenal Hyperplasia– A Rare Cause of Central Precocious Puberty—A Case Report
Abstract
The term ‘Precocious puberty’ refers to the appearance of pubertal signs at an earlier age than established standard. Precocious puberty may be central or peripheral. Central precocious puberty is caused by early maturation of hypothalamic-pituitary-gonadal axis. Peripheral precocious puberty is due to inappropriate secretion of sex steroid hormones from adrenal gland or gonad or from exogenous source and does not involve hypothalamo-pituitary-gonadal axis. We report a rare case where inspite of clinical and hormonal evidence of central precocious puberty ultimately an adrenal pathology was established in a six-year-old boy.
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