Clinical Case Reports (Apr 2020)

Topiramate causing type II renal tubular acidosis: A case and review of the mechanism

  • Michael Chahin,
  • Monique Oye,
  • Sonal Jadeja,
  • Kimberly Sanders,
  • Pramod Reddy

DOI
https://doi.org/10.1002/ccr3.2733
Journal volume & issue
Vol. 8, no. 4
pp. 731 – 733

Abstract

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Abstract Topiramate has a wide array of pharmacologic effects, including proximal renal tubular acidosis (RTA). Clinicians must be wary of the possibility for development of somnolence due to compensatory hyperventilation and cardiac dysrhythmias.

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