Nature Communications (Sep 2016)
Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
Abstract
Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple graft surgeries.